seqmon: Group Sequential Design Class for Clinical Trials

Share:

S4 class object for creating and managing group sequential designs. It calculates the efficacy and futility boundaries at each look. It allows modifying the design and tracking the design update history.

Author
David A Schoenfeld, PhD and Hui Zheng, PhD
Date of publication
2016-10-12 00:43:08
Maintainer
"Hui Zheng, PhD" <hzheng1@mgh.harvard.edu>
License
MIT + file LICENSE
Version
2.1

View on CRAN

Man pages

alphaspend
Function that calculates the upper boundaries for efficacy
alphaspendf
The default alpha spending function
betaspend
Function that calculates the lower boundaries for futility
betaspendf
The default beta spending function
calcBoundaries
Function for calculating the efficacy and futility boundaries
calcBoundaries-methods
~~ Methods for Function 'calcBoundaries' ~~
curtail
Generic function that calculates the probability to declare...
curtailDesign
Function for calculating the probability for efficacy given...
curtailDesign-methods
~~ Methods for Function 'curtailDesign' ~~
getProbabilities
Function that calculates the cumulative probabilities to...
getProbabilities-methods
~~ Methods for Function 'getProbabilities' ~~
plotBoundaries
Function that plots the efficacy and futility boundaries
plotBoundaries-methods
~~ Methods for Function 'plotBoundaries' ~~
printSummary
Function that prints the cumulative probabilities for...
printSummary-methods
~~ Methods for Function 'printSummary' ~~
seqmon
Generic function that calculates the cumulative alpha and...
seqmon-package
seqmon
sequential.design
The sequential design class
sequential.design-class
Class '"sequential.design"'
setAlphaspendfString
Function that Sets the expression of the base alpha spending...
setAlphaspendfString-methods
~~ Methods for Function 'setAlphaspendfString' ~~
setBaseAlphaspendf
Function that sets the base alpha spending function
setBaseAlphaspendf-methods
~~ Methods for Function 'setBaseAlphaspendf' ~~
setBaseBetaspendf
Function that sets the base beta spending function
setBaseBetaspendf-methods
~~ Methods for Function 'setBaseBetaspendf' ~~
setBetaspendfString
Function that sets the expression of the base beta spending...
setBetaspendfString-methods
~~ Methods for Function 'setBetaspendfString' ~~
setCurrentLook
Function that sets the current look number
setCurrentLook-methods
~~ Methods for Function 'setCurrentLook' ~~
setDatestamp
Function that sets the date stamp of the design object
setDatestamp-methods
~~ Methods for Function 'setDatestamp' ~~
setNoncentrality
Function that sets the noncentrality parameter
setNoncentrality-methods
~~ Methods for Function 'setNoncentrality' ~~
setTimes
Function that sets the look times
setTimes-methods
~~ Methods for Function 'setTimes' ~~
updateDesign
Function that updates the design
updateDesign-methods
~~ Methods for Function 'updateDesign' ~~

Files in this package

seqmon
seqmon/NAMESPACE
seqmon/R
seqmon/R/sequential_design_class.R
seqmon/MD5
seqmon/DESCRIPTION
seqmon/man
seqmon/man/setNoncentrality-methods.Rd
seqmon/man/plotBoundaries.Rd
seqmon/man/setBetaspendfString-methods.Rd
seqmon/man/setCurrentLook.Rd
seqmon/man/curtail.Rd
seqmon/man/seqmon.Rd
seqmon/man/setAlphaspendfString.Rd
seqmon/man/curtailDesign-methods.Rd
seqmon/man/sequential.design.Rd
seqmon/man/plotBoundaries-methods.Rd
seqmon/man/setTimes-methods.Rd
seqmon/man/alphaspendf.Rd
seqmon/man/setDatestamp.Rd
seqmon/man/seqmon-package.Rd
seqmon/man/setCurrentLook-methods.Rd
seqmon/man/setBaseAlphaspendf-methods.Rd
seqmon/man/curtailDesign.Rd
seqmon/man/calcBoundaries.Rd
seqmon/man/getProbabilities-methods.Rd
seqmon/man/printSummary.Rd
seqmon/man/updateDesign-methods.Rd
seqmon/man/betaspend.Rd
seqmon/man/setNoncentrality.Rd
seqmon/man/setBaseAlphaspendf.Rd
seqmon/man/setBetaspendfString.Rd
seqmon/man/setDatestamp-methods.Rd
seqmon/man/getProbabilities.Rd
seqmon/man/alphaspend.Rd
seqmon/man/betaspendf.Rd
seqmon/man/printSummary-methods.Rd
seqmon/man/setBaseBetaspendf-methods.Rd
seqmon/man/updateDesign.Rd
seqmon/man/sequential.design-class.Rd
seqmon/man/setTimes.Rd
seqmon/man/calcBoundaries-methods.Rd
seqmon/man/setBaseBetaspendf.Rd
seqmon/man/setAlphaspendfString-methods.Rd
seqmon/LICENSE