haz: Hazard Function for Different Transition Models

In simIDM: Simulating Oncology Trials using an Illness-Death Model

Hazard Function for Different Transition Models

Description

Hazard Function for Different Transition Models

Usage

haz(transition, t, trans)

## S3 method for class 'ExponentialTransition'
haz(transition, t, trans)

## S3 method for class 'WeibullTransition'
haz(transition, t, trans)

## S3 method for class 'PWCTransition'
haz(transition, t, trans)

Arguments

transition	(ExponentialTransition or WeibullTransition) see exponential_transition() or weibull_transition() for details.
t	(numeric) time at which hazard is to be computed.
trans	(integer) index specifying the transition type.

Details

The transition types are:

• 1: Transition from state 0 (stable) to 1 (progression).

• 2: Transition from state 0 (stable) to 2 (death).

• 3: Transition from state 1 (progression) to 2 (death).

Value

The hazard rate for the specified transition and time.

Methods (by class)

• haz(ExponentialTransition): for an exponential transition model.

• haz(WeibullTransition): for the Weibull transition model.

• haz(PWCTransition): for the piecewise constant transition model.

Examples

transition <- exponential_transition(h01 = 1.2, h02 = 1.5, h12 = 1.6)
haz(transition, 0.4, 2)
transition <- exponential_transition(h01 = 1.2, h02 = 1.5, h12 = 1.6)
haz(transition, 0.4, 2)
transition <- weibull_transition(h01 = 1.2, h02 = 1.5, h12 = 1.6, p01 = 2, p02 = 2.5, p12 = 3)
haz(transition, 0.4, 2)
transition <- piecewise_exponential(
  h01 = c(1, 1, 1), h02 = c(1.5, 0.5, 1), h12 = c(1, 1, 1),
  pw01 = c(0, 3, 8), pw02 = c(0, 6, 7), pw12 = c(0, 8, 9)
)
haz(transition, 6, 2)

simIDM documentation built on May 29, 2024, 6:38 a.m.