rmstreg: Adjusted difference/ratio of restricted mean survival times

In surv2sampleComp: Inference for Model-Free Between-Group Parameters for Censored Survival Data

Description

Compares restricted mean survival time between two groups, adjusting for imbalance of baseline factors via a regression model.

Usage

rmstreg(y, delta, x, arm, tau, type="difference", conf.int=0.95)

Arguments

y	The follow-up time.
delta	The censoring indicator, 1=event, and 0=censoring.
x	The covariate matrix. The first colomn of this matrix should be the group indicator, arm (below).
arm	The group indicator, 1/0.
tau	The value indicates the restricted time point on the follow-up time to calculate the restricted mean survival time.
type	The type of the between-group contrast measure: "difference"(default), "ratio" or "lossratio".
conf.int	The level for computation of the confidence intervals. The default is 0.95.

Author(s)

Lu Tian

References

Tian L, Zhao L, Wei LJ. Predicting the restricted mean event time with the subject's baseline covariates in survival analysis. Biostatistics 2014, 15, 222-233.

Examples

D=pbc.sample()
x=cbind(D$group, D$covariates)
rmstreg(D$time, D$status, x, D$group, tau=8, type="difference")

Example output

                   coef     se(coef)           z            p   lower 0.95
intercept  2.6905643719 1.4733790060  1.82611830 0.0678324436 -0.197205415
           0.0084165949 0.2602358592  0.03234218 0.9741991724 -0.501636317
edema     -1.7797656406 0.9925664762 -1.79309465 0.0729577906 -3.725160186
bili      -0.1630732547 0.0420232855 -3.88054511 0.0001042226 -0.245437381
chol      -0.0006939487 0.0005268023 -1.31728490 0.1877431437 -0.001726462
albumin    1.4338384926 0.3916587331  3.66093839 0.0002512932  0.666201481
copper    -0.0067731962 0.0017895288 -3.78490485 0.0001537674 -0.010280608
             upper 0.95
intercept  5.5783341593
           0.5184695063
edema      0.1656289050
bili      -0.0807091287
chol       0.0003385648
albumin    2.2014755037
copper    -0.0032657842

surv2sampleComp documentation built on May 2, 2019, 12:39 a.m.