dti_df: Diffusion tensor imaging data

In tidyfun: Tidy Functional Data Wrangling and Visualization

Diffusion tensor imaging data

Description

Fractional anisotropy (FA) tract profiles for the corpus callosum (cca) and the right corticospinal tract (rcst) from a diffusion tensor imaging (DTI) study of multiple sclerosis patients and healthy controls.

The original data in refund::DTI include additional variables (pasat, Nscans, visit.time) that were not carried over here.

Usage

dti_df

Format

A tibble with 382 rows and 6 columns:

id

(numeric) Subject identifier.

visit

(integer) Visit number.

sex

(factor) "male" or "female".

case

(factor) "control" or "MS" (multiple sclerosis status).

cca

(tfd_irreg) FA tract profiles for the corpus callosum (up to 93 evaluation points, domain 0–1).

rcst

(tfd_irreg) FA tract profiles for the right corticospinal tract (up to 55 evaluation points, domain 0–1).

Details

If you use this data as an example in written work, please include the following acknowledgment: "The MRI/DTI data were collected at Johns Hopkins University and the Kennedy-Krieger Institute."

Source

Data are from the Johns Hopkins University and the Kennedy-Krieger Institute. Also available in a different format as refund::DTI.

References

Goldsmith, J., Bobb, J., Crainiceanu, C., Caffo, B., and Reich, D. (2011). Penalized Functional Regression. Journal of Computational and Graphical Statistics, 20(4), 830–851. \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1198/jcgs.2010.10007")}

Goldsmith, J., Crainiceanu, C., Caffo, B., and Reich, D. (2012). Longitudinal Penalized Functional Regression for Cognitive Outcomes on Neuronal Tract Measurements. Journal of the Royal Statistical Society: Series C, 61(3), 453–469. \Sexpr[results=rd]{tools:::Rd_expr_doi("10.1111/j.1467-9876.2011.01031.x")}

See Also

chf_df for another example dataset, vignette("x04_Visualization", package = "tidyfun") for usage examples.

Other tidyfun datasets: chf_df

Examples

dti_df

library(ggplot2)
dti_df |>
  dplyr::filter(visit == 1) |>
  tf_ggplot(aes(tf = cca, color = case)) +
  geom_line(alpha = 0.3)

tidyfun documentation built on April 24, 2026, 5:06 p.m.