Freireich: Acute Leukemia data from Freireich et al (1963)

In timeEL: Time to Event Analysis via Empirical Likelihood Inference

Acute Leukemia data from Freireich et al (1963)

Description

In this study there were 21 pairs of subjects, and within each pair one subject received 6-mercaptopurine (6-MP) and one got placebo. The data are right censored. See also Gehan (1965) and Thomas & Grunkemeier (1975) who used the data as an illustrative example (ignoring the pairing).

Usage

Freireich

Format

A data frame with 42 rows and 3 variables:

time

time in remission (in weeks)

status

event status, 1 is relapse, 0 is censored

group

treatment group: 0 (placebo) or 1 (6-MP)

Source

Data listed in Section 5 in Thomas & Grunkemeier (1975) and Section 11 in Gehan (1965)

References

Freireich et al (1963) Blood 21(6):699-716

Gehan (1965) Biometrika 52:203-223

Thomas & Grunkemeier (1975) JASA 70(352): 865-871

timeEL documentation built on Sept. 12, 2024, 9:35 a.m.