tipmap: Tipping Point Analysis for Bayesian Dynamic Borrowing

Tipping point analysis for clinical trials that employ Bayesian dynamic borrowing via robust meta-analytic predictive (MAP) priors. Further functions facilitate expert elicitation of a primary weight of the informative component of the robust MAP prior and computation of operating characteristics. Intended use is the planning, analysis and interpretation of extrapolation studies in pediatric drug development, but applicability is generally wider.

Package details

AuthorChristian Stock [aut, cre] (<https://orcid.org/0000-0002-3493-3234>), Morten Dreher [aut], Emma Torrini [ctb], Boehringer Ingelheim Pharma GmbH & Co. KG [cph, fnd]
MaintainerChristian Stock <christian.stock@boehringer-ingelheim.com>
LicenseApache License 2.0
Version0.5.2
URL https://github.com/Boehringer-Ingelheim/tipmap
Package repositoryView on CRAN
Installation Install the latest version of this package by entering the following in R:
install.packages("tipmap")

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tipmap documentation built on Aug. 14, 2023, 5:09 p.m.