trioGxE: A data smoothing approach to explore and test gene-environment interaction in case-parent trio data

The package contains functions that 1) estimates gene-environment interaction between a SNP and a continuous non-genetic attribute by fitting a generalized additive model to case-parent trio data, 2) produces graphical displays of estimated interaction, 3) performs permutation test of gene-environment interaction; 4) simulates informative case-parent trios.

Author
Ji-Hyung Shin <shin@sfu.ca>, Brad McNeney <mcneney@sfu.ca>, Jinko Graham <jgraham@sfu.ca>
Date of publication
2013-04-03 01:39:24
Maintainer
Ji-Hyung Shin <shin@sfu.ca>
License
GPL-2
Version
0.1-1

View on CRAN

Man pages

hypoTrioDat
Simulated data for a hypothetical example
plot.trioGxE
Graphical display of gene-environment interaction between a...
test.trioGxE
Test of gene-environment interaction between a SNP and a...
trioGxE
Generalized additive model estimation of gene-environment...
trioGxE-internal
Internal pirls.trio Functions
trioSim
Simulate informative case-parent trios

Files in this package

trioGxE
trioGxE/MD5
trioGxE/R
trioGxE/R/trioSim.R
trioGxE/R/trioplot_mgcv.R
trioGxE/R/trioGxE_fcns.R
trioGxE/R/trioGxE.R
trioGxE/R/test.trioGxE.R
trioGxE/R/plot.trioGxE.R
trioGxE/R/CubicSplineBasisFuncs.R
trioGxE/NAMESPACE
trioGxE/man
trioGxE/man/trioSim.Rd
trioGxE/man/trioGxE.Rd
trioGxE/man/trioGxE-internal.Rd
trioGxE/man/test.trioGxE.Rd
trioGxE/man/plot.trioGxE.Rd
trioGxE/man/hypoTrioDat.Rd
trioGxE/DESCRIPTION
trioGxE/data
trioGxE/data/hypoTrioDat.txt.gz