| shilong | R Documentation |
The original SHIdat data set contains an anonymized excerpt of data from the SHIVA01 trial. This was the first randomized clinical trial that aimed at comparing molecularly targeted therapy based on tumor profiling (MTA) versus conventional therapy (CT) for advanced cancer. Patients were randomly assigned to receive the active or control treatment and may switch to the other arm or subsequent anti-cancer therapy upon disease progression. The restructured data is in the long format.
idThe patient's identifier
tstartThe start of the time interval
tstopThe end of the time interval
eventWhether the patient died at the end of the interval
agerandThe patient's age (in years) at randomization
sex.fThe patients' gender, either Male or Female
tt_LnumThe number of previous lines of treatment
rmh_alea.cThe Royal Marsden Hospital score segregated into two categories
pathway.fThe molecular pathway altered (the hormone receptors pathway, the PI3K/ AKT/mTOR pathway, and the RAF/MEK pathway)
bras.fThe patient's randomized arm, either MTA or CT
psThe ECOG performance status
ttcThe presence of concomitant treatments
tranThe use of platelet transfusions
dpdThe relative day of a potential progression
dcoThe relative day of treatment switching
adyThe relative day of the latest news
dcutThe relative day of administrative cutoff
pdWhether the patient had disease progression
coWhether the patient switched treatment
shilong
An object of class data.frame with 602 rows and 19 columns.
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