trim: Trim data for plotting/reporting

In vaccine: Statistical Tools for Immune Correlates Analysis of Vaccine Clinical Trial Data

Trim data for plotting/reporting

Description

Removes a subset of estimates returned by est_ce

Usage

trim(ests, dat, quantiles, placebo = FALSE)

Arguments

ests	An object of class "vaccine_est" returned by est_ce.
dat	The data object originally passed into est_ce.
quantiles	A vector of length 2 representing the quantiles of the marker distribution at which to trim the data; if, for example, quantiles=c(0.1,0.9) is specified, values outside the 10 (weighted) quantiles of the marker distribution will be trimmed.
placebo	Boolean; if TRUE, quantiles are computed based on the marker distribution in the placebo arm instead of the vaccine arm

Value

A modified copy of ests with the data trimmed.

Examples

data(hvtn505)
dat <- load_data(time="HIVwk28preunblfu", event="HIVwk28preunbl", vacc="trt",
                 marker="IgG_V2", covariates=c("age","BMI","bhvrisk"),
                 weights="wt", ph2="casecontrol", data=hvtn505)
ests_cox <- est_ce(dat=dat, type="Cox", t_0=578)
ests_cox_tr <- trim(ests_cox, dat=dat, quantiles=c(0.05,0.95))
plot_ce(ests_cox_tr, density_type="kde", dat=dat)

vaccine documentation built on April 4, 2025, 12:12 a.m.