waffect: A package to simulate constrained phenotypes under a disease model H1

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waffect (pronounced 'double-u affect' for 'weighted affectation') is a package to simulate phenotypic (case or control) datasets under a disease model H1 such that the total number of cases is constant across all the simulations (the constrain in the title). The package also makes it possible to generate phenotypes in the case of more than two classes, so that the number of phenotypes belonging to each class is constant across all the simulations. waffect is used to assess empirically the statistical power of Genome Wide Association studies.

Author
Gregory Nuel and Vittorio Perduca
Date of publication
2012-04-11 13:32:12
Maintainer
G. Nuel <gregory.nuel@parisdescartes.fr>
License
GPL (>= 3)
Version
1.2

View on CRAN

Man pages

map
SNP description in MAP format
p1_H0
Signal of association of the statistic S1 under H0
p1_H1
Signal of association of the statistic S1 under H1
p2_H0
Signal of association of the statistic S2 under H0
p2_H1
Signal of association of the statistic S2 under H1
ped
Genotypic dataset in PED format
waffect
Simulation of phenotypes in the binary (case/control) and...
waffectbin
Low level function for simulating binary phenotypes.
waffect-package
A package to simulate constrained phenotypes under a disease...

Files in this package

waffect
waffect/MD5
waffect/vignettes
waffect/vignettes/waffect-tutorial.Rnw
waffect/vignettes/biblio.bib
waffect/src
waffect/src/xdouble.h
waffect/src/waffect.h
waffect/src/waffect.cpp
waffect/src/Makevars.win
waffect/src/Makevars
waffect/R
waffect/R/waffectbin.R
waffect/R/waffect.R
waffect/NAMESPACE
waffect/man
waffect/man/waffectbin.Rd
waffect/man/waffect.Rd
waffect/man/waffect-package.Rd
waffect/man/ped.Rd
waffect/man/p2_H1.Rd
waffect/man/p2_H0.Rd
waffect/man/p1_H1.Rd
waffect/man/p1_H0.Rd
waffect/man/map.Rd
waffect/inst
waffect/inst/doc
waffect/inst/doc/waffect-tutorial.Rnw
waffect/inst/doc/waffect-tutorial.pdf
waffect/inst/CITATION
waffect/DESCRIPTION
waffect/data
waffect/data/ped.txt.gz
waffect/data/p2_H1.txt.gz
waffect/data/p2_H0.txt.gz
waffect/data/p1_H1.txt.gz
waffect/data/p1_H0.txt.gz
waffect/data/map.txt.gz