Rdata: Simulation data for Genetic association models for...

In xlink: Genetic Association Models for X-Chromosome SNPS on Continuous, Binary and Survival Outcomes

Description

A simulated dataset containing 400 observations. The variables list as follows:

Usage

data(Rdata)

Format

A data frame with 400 rows and 17 variables.

Details

• ID. Identification number.

• OS. Survival indicator, 1 for death, 0 for censoring.

• OS_time. Duration time of survival.

• gender. Binary value 0,1 with P(x=1)=0.5 and hazard ratio is 1.

• Age. Uniform distribution in [20,80] and hazard ratio is 1.02.

• Smoking. Binary value 0,1 with P(x=1)=0.3 and hazard ratio is 1.2.

• Treatment. Binary value 0,1 with P(X=1)=0.3 and hazard ratio is 1.2.

• snp_1. True type in coxph model is 'XCI', minor allele frequency is 0.2, hazard ratio is 1.5.

• snp_2. True type in coxph model is 'XCI-E', minor allele frequency is 0.3, hazard ratio is 1.5.

• snp_3. True type in coxph model is 'XCI-S', minor allele frequency is 0.4, hazard ratio is 1.5.

• snp_4. True type in coxph model is 'XCI', minor allele frequency is 0.3, hazard ratio is 1.

• snp_5. True type in coxph model is 'XCI-E', minor allele frequency is 0.1, hazard ratio is 1.

• snp_6. True type in coxph model is 'XCI', minor allele frequency is 0.2, hazard ratio is 1.

• snp_7. True type in coxph model is 'XCI', minor allele frequency is 0.15, hazard ratio is 1.

• snp_8. True type in coxph model is 'XCI-E', minor allele frequency is 0.1, hazard ratio is 1.

• snp_9. True type in coxph model is 'XCI', minor allele frequency is 0.2, hazard ratio is 1.

• snp_10. True type in coxph model is 'XCI', minor allele frequency is 0.15, hazard ratio is 1.

xlink documentation built on Aug. 21, 2019, 1:05 a.m.