IncrementsNumDoseLevels-class: 'IncrementsNumDoseLevels'

Description Usage Arguments Slots Examples

Description

[Stable]

Usage

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IncrementsNumDoseLevels(maxLevels = 1, basisLevel = "last")

Arguments

maxLevels

see below.

basisLevel

see below.

Slots

maxLevels

(count)
corresponding to the number of maximum dose levels to increment for the next dose. It defaults to 1, which means that no dose skipping is allowed - the next dose can be maximum one level higher than the current dose.

basisLevel

(string)
corresponding to the dose level used to increment from. It can take two possible values last or max. If last (default) is specified the increments is applied to the last given dose and if max is specified the increment is applied from the max given dose level.

Examples

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# In this example we define a rule for dose increments which would allow:
# Maximum skip one dose level, that is 2 dose levels higher than the last dose
# given.
# Maximum increment is explicitly defined as:
increments <- IncrementsNumDoseLevels(maxLevels = 2, basisLevel = "last")
# Since the default method is based on the last dose given,
# maximum increment can also be defined as:
increments <- IncrementsNumDoseLevels(maxLevels = 2)

0liver0815/onc-crmpack-test documentation built on Feb. 19, 2022, 12:25 a.m.