Description Usage Arguments Slots Examples
StoppingMTDCV
is a class for stopping rule based on precision of MTD
which is calculated as the coefficient of variation (CV) of the MTD.
1 | StoppingMTDCV(target = 0.3, thresh_cv = 40)
|
target |
( |
thresh_cv |
( |
target
(proportion
)
toxicity target of MTD.
thresh_cv
(number
)
threshold for CV to be considered accurate enough
to stop the trial.
1 2 3 | # Stopping the study if the MTD estimation is precise enough, i.e. if robust
# coefficient of variation of the MTD is below 40%.
my_stopping <- StoppingMTDCV(target = 0.3, thresh_cv = 40)
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