StoppingMTDCV-class: 'StoppingMTDCV'

Description Usage Arguments Slots Examples

Description

[Experimental]

StoppingMTDCV is a class for stopping rule based on precision of MTD which is calculated as the coefficient of variation (CV) of the MTD.

Usage

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StoppingMTDCV(target = 0.3, thresh_cv = 40)

Arguments

target

(proportion)
see slot definition.

thresh_cv

(number)
see slot definition.

Slots

target

(proportion)
toxicity target of MTD.

thresh_cv

(number)
threshold for CV to be considered accurate enough to stop the trial.

Examples

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# Stopping the study if the MTD estimation is precise enough, i.e. if robust
# coefficient of variation of the MTD is below 40%.
my_stopping <- StoppingMTDCV(target = 0.3, thresh_cv = 40)

0liver0815/onc-crmpack-test documentation built on Feb. 19, 2022, 12:25 a.m.