README.md

In 2eding/GRAMMAR: Generalized Renown Analysis of Molecular variance for Mixed model Analysis R package (GRAMMAR)

GAMMAR

Generalized Renown Analysis of Molecular variance for Mixed model Analysis R package

Usage

Step 1. Install and load the package

library(devtools) install_github("2eding/GAMMAR") library(GAMMAR)

Step 2. Input data

X <- as.matrix(data.table::fread("X_rightdim.txt")) Y <- as.matrix(data.table::fread("Y_rightdim.txt")) data.table::fread <= This package is useful for input large data X_rightdim.txt is snp data * Y_rightdim.txt is gene expression data

Step 3. Calculate the kinship

K <- Kinship(X)

Step 4. Calculate the variance components

VC <- varComp(K, Y, X)

Step 5. Run GAMMAR

run <- run_grammar(K, Y, X, VC, max_itr = 4, num.parallel = 4, outPath = "./test/", outName = "result.txt")

Publication

http://doi.org/10.5391/IJFIS.2020.20.3.1

2eding/GRAMMAR documentation built on Jan. 18, 2024, 6 a.m.