diffusionData: diffusionData

In Amy3100/receptor2tfDiffusion: This package calculate single-sample network connectivity

Description

Network connectivity between receptors and TFs using diffusion

Usage

data(diffusionData)

Format

An object of class "list";

Variable "M": Data frame containing expression data for 24501 genes and 54 samples. Variable "sampleSheet": Data frame containing information on whether patients responded or resistant to the anti-TNF treatment. 54 samples and 12 phenotype columns.

Details

Gene expression data from IBD patients with matching signalling network and candidate receptors-transcription factors.

References

Singh et al. (2021) ....

Examples

data(diffusionData)
receptors <- diffusionData$receptors[1:4]
TF <- diffusionData$TFs[1]
nodeW <- diffusionData$M[,34]
network <- diffusionData$network
diffusion_curve <- signalOnNetwork(network,nodeW,outputNode = TF,inputNode = receptors)

Amy3100/receptor2tfDiffusion documentation built on Dec. 17, 2021, 8:47 a.m.