CloneDeMix_core: Decomposing the subclonal structure of tumors with two-way...

Description Usage Arguments Value Author(s)

View source: R/CloneDeMix_core.R

Description

The core function of CloneDeMix.

Usage

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CloneDeMix_core(dataX, threshold = 10^-5, CNVstate = c(0:4), numbG = 4,
  baseline = NULL, iterationC = 10^3)

Arguments

dataX

DNA count of a tumor sample.

threshold

The threhold of convergence. Default is 10^-5.

CNVstate

A vector of considered copy number state.

numbG

The number of subclones.

baseline

A vector of length s. It's a count profile from the paired normal sample. If it's empty, the baseline is calculated from sample mean.

iterationC

Maximum number of iterations. Default is 1000.

Value

A list containing MCP vector, the weight of copy number state, error rate, AIC, and BIC.

Author(s)

An-Shun Tai daansh13@gmail.com


AshTai/CloneDeMix documentation built on May 28, 2019, 11:04 a.m.