example.model: kmFit example model results

example.modelR Documentation

kmFit example model results

Description

A dataset containing linear mixed effects model results with and without genetic kinship correction. Raw data were obtained from the kimma package.

Usage

example.model

Format

List of 6: Results for linear mixed effects (lme) or linear mixed effects model with kinship relatedness (lmerel) for ~ virus*asthma + (1|ptID)

  1. lme/lmerel A data frame with 1000 rows and 10 columns

    model

    character. Model name.

    gene

    character. ENSEMBL gene ID.

    variable

    character. Variable name.

    estimate

    numeric. Model estimate, i.e. log fold change.

    pval

    numeric. Significance estimate.

    FDR

    numeric. FDR corrected signficant estimate.

    hgnc_symbol

    character. Current HUGO/HGNC gene symbol.

    Previous symbols

    comma separated character. Previous HUGO/HGNC gene symbols, if any.

    Alias symbols

    comma separated character. Alias HUGO/HGNC gene symbols, if any.

    gene_biotype

    character. Gene biotype. All protein coding in this data set.

  2. lme.contrast/lmerel.contrast A data frame with 8000 rows and 15 columns

    model

    character. Model name.

    gene

    character. ENSEMBL gene ID.

    variable

    character. Variable name.

    contrast_ref

    character. Model name.

    contrast_lvl

    character. Model name.

    estimate

    numeric. Model estimate, i.e. log fold change.

    pval

    numeric. Significance estimate.

    FDR

    numeric. FDR corrected signficant estimate.

    std.error

    numeric. Dtandard error.

    df

    numeric. Degrees of freedom.

    statistic

    numeric. T statistic.

    hgnc_symbol

    character. Current HUGO/HGNC gene symbol.

    Previous symbols

    comma separated character. Previous HUGO/HGNC gene symbols, if any.

    Alias symbols

    comma separated character. Alias HUGO/HGNC gene symbols, if any.

    gene_biotype

    character. Gene biotype. All protein coding in this data set.

  3. lme.fit/lmerel.fit A data frame with 1000 rows and 11 columns

    model

    character. Model name.

    gene

    character. ENSEMBL gene ID.

    sigma

    numeric. Estimated standard deviation of the errors, ie residual standard deviation.

    AIC

    numeric. Akaike information criterion.

    BIC

    numeric. Bayesian information criterion.

    Rsq

    numeric. R-squared.

    adj_Rsq

    numeric. Adjusted R-squared.

    hgnc_symbol

    character. Current HUGO/HGNC gene symbol.

    Previous symbols

    comma separated character. Previous HUGO/HGNC gene symbols, if any.

    Alias symbols

    comma separated character. Alias HUGO/HGNC gene symbols, if any.

    gene_biotype

    character. Gene biotype. All protein coding in this data set.

Source

https://github.com/altman-lab/P259_pDC_public

References

Dill-McFarland et al. 2021. Eosinophil-mediated suppression and Anti-IL-5 enhancement of plasmacytoid dendritic cell interferon responses in asthma. J Allergy Clin Immunol. In revision


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