bg.adjust: Background adjustment (internal function)

View source: R/bg.R

bg.adjustR Documentation

Background adjustment (internal function)

Description

An internal function to be used by bg.correct.rma.

Usage

bg.adjust(pm, n.pts = 2^14, ...)
bg.parameters(pm, n.pts = 2^14)

Arguments

pm

a pm matrix

n.pts

number of points to use in call to density.

...

extra arguments to pass to bg.adjust.

Details

Assumes PMs are a convolution of normal and exponential. So we observe X+Y where X is background and Y is signal. bg.adjust returns E[Y|X+Y, Y>0] as our background corrected PM. bg.parameters provides ad hoc estimates of the parameters of the normal and exponential distributions.

Value

a matrix

See Also

bg.correct.rma


Bioconductor/affy documentation built on July 21, 2023, 5:23 p.m.