DeNoise: Denoise a reference Seurat Object

In BruceRheaume/CellTools: What the Package Does (One Line, Title Case)

Denoise a reference Seurat Object

Description

This function denoises, or removes sources of noise, which can affect downstream intergration analyses

Usage

DeNoise(ref, lab, coef = 1.5)

Arguments

ref	Reference Seurat object with pre-calculated UMAP
lab	The reference label to treat as clusters. Default is "seurat_clusters"
coef	The coefficient to multiply by the IQR. Default is 1.5

Value

Returns a Seurat object with a new slot called "denoise"

References

Rheaume, B. A., & Trakhtenberg, E. F. (2022). Self-learning algorithm for denoising and advancing the integration of scRNA-seq datasets improves the identification of resilient and susceptible retinal ganglion cell types bioRxiv.

BruceRheaume/CellTools documentation built on April 24, 2022, 7:03 p.m.