get_r0: Reference bias due to alignment

In Catalysta/ASEtestTools: ANEVA Dosage Outlier Test

Description

This function is designed to estimate the reference ratio in the absence of any regulatory difference; that is, the reference bias due to alignment. This is done by obtaining the median ratio between eh1 and eh2 across the top 20

Usage

get_r0(ASEdat, eh1 = "refCount", eh2 = "altCount")

Arguments

ASEdat	Dataframe containing reference and alternative count data.
eh1	A string with the column name of the reference count data
eh2	A string with the column name of the alternative count data

Value

A numeric estimate of the reference bias r0 for the given library.

Catalysta/ASEtestTools documentation built on Oct. 10, 2021, 7:44 a.m.