Beta_est: Computes the allelic frequency

Description Usage Arguments Details Value References See Also

Description

Computes the allelic frequency using the Best Linear Unbiased Estimator (BLUE) and the kinship matrices

Usage

1
Beta_est(lstfki)

Arguments

lstfki

MQLS object computed by the function Deco.kinf.

Details

The function uses the Best Linear Unbiased Estimator (BLUE) and the family kinship matrices to compute the allelic frequency. For the details, see T. Thornton et al.,(2007).

Value

Return the allelic frequency.

References

Thornton T and McPeek MS: Case-control association testing with related individuals: a more powerful quasi-likelihood score test. Am J Hum Genet 2007, 81:321,337.

Bourgain C, Hoffjan S, Nicolae R, Newman D, Steiner L, Walker K, Reynolds R, Ober C and McPeek MS:Novel case-control test in a founder population identifies P-selectin as an atopy-susceptibility locus. Am J Hum Genet 2003, 73:612,626.

See Also

Deco.kinf


CroteauCRIUSMQ/EMQLS.test documentation built on May 6, 2019, 12:52 p.m.