EMQLS.test-package: Extension of Maximum Quasi-likelihood Score test
In CroteauCRIUSMQ/EMQLS.test: Extension of MQLS test
Description
Details
Author(s)
References
See Also
Description
Package implements the Maximum Quasi-likelihood Score test proposed by T. Thornton et al., (2004) and an extension of the test proposed by M. Nguile-Maka et al., (under review).
Details
Package: EMQLS.test
Type: Package
Version: 1.0
Date: 2015-04-02
License: GPL-2
The package EMQLS.test implements the Maximum Quasi-likelihood Score test proposed by T. Thornton et al., (2004) and an extension of the test proposed by M. Nguile-Maka et al.,(under review). EMQLS permits to detect the association between SNPs and the complex phenotypes in case-control samples where individuals are related in the stratum (Families). The extension proposed permits to include the endophenotype and her SNP associated, in the aim to increase the test power. The package also proposes other functions like the function to compute the posterior kinship matrices KinshAposterior, minor allelic frequency via the best linear unbiased estimator (BLUE) (Beta_est) EMQLS test (MQLS.test1,MQLS.test2). Package uses the kinship function of the package kinship2 to estimate the a posterior kinship matrix and the function pseudoinverse of the package corpcor to estimate the pseudo-inverse the kinship matrix when it has the problem of the singularity matrix.
Author(s)
Moliere Nguile Makao & Alexandre Bureau.
Maintainer: Moliere Nguile Makao <moliere.nguile@gmail.com>
References
Timothy Thornton and Mary sara McPeek Case-Control Association Testing with Related Individuals: A More Powerful Quasi-likelihood Score Test American journal of human genetics vol 81 August 2007
Alexandre Bureau, Jordie Croteau, Yvon C. Chagnon, Marc-Andre Roy and Michel Maziade. Exension of the generalized disequilibrium test to polytomous phenotypes and two-locus models Genetics DOI: 10.3389/fgene.2014.00258.
Moliere Nguile-Makao, Alexandre Bureau. Extension of the MQLS test: Application at Joint modelling of the complex diseases and endophenotypes to characterize genes and their interactions under review
See Also
Beta_est, Deco.kinf, GenoCod_Gen, KinshAposterior, kinshAprior, Mqls.test1, Mqls.test2
CroteauCRIUSMQ/EMQLS.test documentation built on May 6, 2019, 12:52 p.m.
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Description Details Author(s) References See Also
Description
Package implements the Maximum Quasi-likelihood Score test proposed by T. Thornton et al., (2004) and an extension of the test proposed by M. Nguile-Maka et al., (under review).
Details
| Package: | EMQLS.test |
| Type: | Package |
| Version: | 1.0 |
| Date: | 2015-04-02 |
| License: | GPL-2 |
The package EMQLS.test implements the Maximum Quasi-likelihood Score test proposed by T. Thornton et al., (2004) and an extension of the test proposed by M. Nguile-Maka et al.,(under review). EMQLS permits to detect the association between SNPs and the complex phenotypes in case-control samples where individuals are related in the stratum (Families). The extension proposed permits to include the endophenotype and her SNP associated, in the aim to increase the test power. The package also proposes other functions like the function to compute the posterior kinship matrices KinshAposterior, minor allelic frequency via the best linear unbiased estimator (BLUE) (Beta_est) EMQLS test (MQLS.test1,MQLS.test2). Package uses the kinship function of the package kinship2 to estimate the a posterior kinship matrix and the function pseudoinverse of the package corpcor to estimate the pseudo-inverse the kinship matrix when it has the problem of the singularity matrix.
Author(s)
Moliere Nguile Makao & Alexandre Bureau.
Maintainer: Moliere Nguile Makao <moliere.nguile@gmail.com>
References
Timothy Thornton and Mary sara McPeek Case-Control Association Testing with Related Individuals: A More Powerful Quasi-likelihood Score Test American journal of human genetics vol 81 August 2007
Alexandre Bureau, Jordie Croteau, Yvon C. Chagnon, Marc-Andre Roy and Michel Maziade. Exension of the generalized disequilibrium test to polytomous phenotypes and two-locus models Genetics DOI: 10.3389/fgene.2014.00258.
Moliere Nguile-Makao, Alexandre Bureau. Extension of the MQLS test: Application at Joint modelling of the complex diseases and endophenotypes to characterize genes and their interactions under review
See Also
Beta_est, Deco.kinf, GenoCod_Gen, KinshAposterior, kinshAprior, Mqls.test1, Mqls.test2
R Package Documentation
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Note that we can't provide technical support on individual packages. You should contact the package authors for that.
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