Description Usage Format References Examples
We simulated 300 unphased European genotypes. For that matter, we used the HAPGEN2 software and the 1000 genome phase 3 reference data. The simulated regions are located on the 22 chromosome between the nucleotide positions 16061016 (rs9617528) and 19976834 (rs887201). Only the markers of the Affymetrix 500K are included.
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An integer matrix with 300 rows and 450 columns. The SNP rsIDs
and positions, in addition to their reference and alternate alleles, are
combined in colnames(X)
.
Su, Z., Marchini, J., & Donnelly, P. (2011). HAPGEN2: Simulation of multiple disease SNPs. Bioinformatics, 27(16), 2304–2305.
Consortium, T. 1000 G. P., Auton, A., Abecasis, G. R., Altshuler (Co-Chair), D. M., Durbin (Co-Chair), R. M., Abecasis, G. R., … Abecasis, G. R. (2015). A global reference for human genetic variation. Nature, 526, 68.
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