BRef: Reference profiles from circulating immune cells.

In GfellerLab/EPIC: Estimate the Proportion of Immune and Cancer cells

Reference profiles from circulating immune cells.

Description

A dataset containing the reference profiles obtained from immune cell samples of B cells, CD4 T cells, CD8 T cells, Monocytes, NK cells and Neutrophils, purified from PBMC or whole blood.

Usage

BRef

Format

A list of 3 elements:

$refProfiles, $refProfiles.var

Matrices (nGenes x nRefCells) of the gene expression (in TPM counts) from the reference cells and the variability of this gene expression for each gene and each cell type

$sigGenes

A list of signature genes used to deconvolve the cell proportions

Details

The original samples were obtained from healthy donors and donors after influenza vaccination or with diabetes, sepsis or multiple sclerosis.

Source

1. https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-64655,

2. https://www.ebi.ac.uk/arrayexpress/experiments/E-GEOD-60424/,

3. http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE51984

GfellerLab/EPIC documentation built on July 22, 2023, 2:06 a.m.