sample_pop: Sample a patient population

In InnovationValueInitiative/IVI-RA: The IVI-RA model

Description

Sample a patient population for use in the individual patient simulation (sim_iviRA).

Usage

sample_pop(n = 1, type = c("homog", "heterog"), age_mean = 55,
  age_sd = 13, male_prop = 0.21, haq0_mean = 1.5, haq0_sd = 0.7,
  wtmale = 89, wtfemale = 75, prev_dmards_mean = 3.28,
  prev_dmards_sd = 1.72, das28_mean = 6, das28_sd = 1.2,
  sdai_mean = 43, sdai_sd = 13, cdai_mean = 41, cdai_sd = 13,
  cor_das28_sdai = 0.86, cor_das28_cdai = 0.86, cor_das28_haq = 0.38,
  cor_sdai_cdai = 0.94, cor_sdai_haq = 0.34, cor_cdai_haq = 0.34)

Arguments

n	Number of samples.
type	Should male and female patients be heterogeneous or homogeneous. Default is homogeneous.
age_mean	Mean age.
age_sd	Standard deviation of age.
male_prop	Proportion male.
haq0_mean	Mean baseline HAQ (i.e., HAQ at the start of the model) score.
haq0_sd	Standard deviation of baseline HAQ score.
wtmale	Male weight.
wtfemale	Female weight.
prev_dmards_mean	Mean number of previous DMARDs.
prev_dmards_sd	Standard deviation of number of previous DMARDs.
das28_mean	Mean of DAS28.
das28_sd	Standard deviation of DAS28.
sdai_mean	Mean of SDAI.
sdai_sd	Standard deviation of SDAI.
cdai_mean	Mean of CDAI.
cdai_sd	Standard deviation of CDAI.
cor_das28_sdai	Correlation between DAS28 and SDAI.
cor_das28_cdai	Correlation between DAS28 and CDAI.
cor_das28_haq	Correlation between DAS28 and baseline HAQ.
cor_sdai_cdai	Correlation between SDAI and CDAI.
cor_sdai_haq	Correlation between SDAI and HAQ.
cor_cdai_haq	Correlation between CDAI and HAQ.

Value

Matrix of patient characteristics. One row for each patient and one column for each variable. Current variables are:

age

Age in years.

male

1 = male, 0 = female.

weight

Patient weight in KG.

prev_dmards

Number of previous DMARDs.

das28

DAS28 score.

sdai

SDAI score.

cdai

CDAI score.

haq0

Baseline HAQ score.

Examples

sample_pop(n = 10, type = "heterog", age_mean = 50)

InnovationValueInitiative/IVI-RA documentation built on Oct. 20, 2020, 10:02 p.m.