Description Usage Arguments Value
View source: R/MiXcan_association.R
Association analysis with MiXcan predicted gene expression levels
1 | MiXcan_association(MiXcan_predicted_expr, covariates, outcome, family)
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MiXcan_predicted_expr: |
A N by 2 matrix indicating the predicted gene expression levels in two cell types. If a non-specific model is used for prediction, the predicted values should be the same in two cell types. |
covariates: |
A N by P matrix for the covariates in association analysis. |
outcome: |
The dependent variable of the association analysis. It can be continuous, categorical and count variables, and modeled through generalized linear models (GLM). |
family: |
Same as the family object used in GLM. |
A tibble showing the estimate, standard error, p value for cell 1 and 2 and the combined p value using the Cauchy combination.
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