Description Usage Arguments Value
A function to pre-process the raw input data by applying the Haldane-Anscombe correction, and then convert the raw data into a structure which contains necessary information for analysis, i.e., Chromosome, GeneID, Gene_name, genomic position, and the logit transformation of the ASE ratios for normal (O1) and abnormal (O2) groups. This function can be easily modified to apply to other similar real data structures.
1 |
norm.M |
A |
norm.P |
A |
abnorm.M |
A |
abnorm.P |
A |
rep |
A vector indicates the number of biological replicates for normal and abnormal groups. |
A data.frame
in the structure that would be needed for analysis by hmmASE method.
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