View source: R/calculate_tissue_vectors.R
This function takes the SNP annotations outputted from the annotate_snps function and the provided annotation weigths to yield a set of tissue scores that indicate how much of the fine-mapping/association signal can be apportioned to each tissue/cell type
1 2 3 4 5 6 7 | calculate_tissue_vectors(
snp.annotated.df,
tissue_annotation_file,
genomic_annotation_file,
ess.annot = NULL,
ess.file = NULL
)
|
snp.annotated.df |
Dataframe of annotated SNP info, this is output from annotate_snps function |
tissue_annotation_file |
Path to the input file of tissue annotation names and weights |
genomic_annotation_file |
Path to the input file of genomic annotation names and weights] |
ess.annot |
Optional: Name of genomic annotation requiring specificity scores (e.g. "coding") |
ess.file |
Optional: Path to the specificity score file for ess.annot, (e.g. expression specificity scores for coding annotations) |
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