Cel_aging_1: Cel_YA_1

Cel_aging_1R Documentation

Cel_YA_1

Description

Transcriptomic data from C. elegans aging adults/ rrf-3 mutants .

Usage

Cel_aging_1

Format

An object of class list of length 7.

Details

One (unpublished) time series is included in this dataset.

  • Byrne et al.

The gene expression matrix is log(X + 1) of quantile-normalized raw data, filtered to keep genes with a strong aging signal.

Format

A list with :

  • ⁠$g⁠: The gene expression matrix (genes as rows, samples as columns)

  • ⁠$p⁠: A dataframe of phenotypic data on the samples, usually :

    • sname : The sample names (and colnames of the gene expression matrix).

    • age : Sample developmental age. May be scaled to join multiple datasets.

    • cov : A factor separating the samples into groups if needed (e.g multiple datasets, batches); else NULL.

    • age_ini : Sample chronological age, as given in the literature.

    • accession : Sample accession ID for GEO/ArrayExpress.

  • ⁠$geim_params⁠: A list of elements needed for the gene expression interpolation model :

    • ⁠$formula⁠ : the model formula.

    • ⁠$method⁠ : the model type (eg. gam, glm).

    • ⁠$dim_red⁠ : the dimension reduction method to use (pca, ica).

    • ⁠$nc⁠: The number PCA/ICA components to use in the model.

  • ⁠$t.unit⁠: the time series unit (e.g 'hours').

  • ⁠$cov.levels⁠: a named list of potential covariate with the level to interpolate as.

  • ⁠$metadata⁠: a named list of extra metadata (e.g organism, profiling technology).

Source

GSE93826

References

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LBMC/wormRef documentation built on April 6, 2023, 12:31 p.m.