calculate_RECIST_response: Calculates whether data indicates a complete response by...

In LisaHopcroft/CTutils: Helpful Functions for Clinical Trial Data Analysis at SCTRU (Public Health Scotland)

Description

This function takes tumour measurement data and calculates the RECIST outcome. It calculates a response for one timepoint measurement against the baseline. If multiple timepoint measurements are to be compared to a baseline, then this function will need to be run multiple times. It presumes that the data that are passed here are clean (i.e., all data are present, none are missing; all diameters add up to the sum etc.). The data in should also have a column that represents the minimum sum of tumour diameters (across all timepoints) for each patient.

Usage

calculate_RECIST_response(
  this_data,
  id_variable,
  baseline_diam,
  baseline_sum,
  min_sum = NULL,
  timepoint_diam,
  timepoint_sum,
  this_function = NA,
  label_string = "RECIST"
)

Arguments

this_data	The tibble in which the column exists.
id_variable	The column that defines each patient (i.e., the patient ID)
baseline_diam	The variable that represents the individual diameters at baseline
baseline_sum	The variable that represents the sum at baseline
min_sum	The variable that represents the smallest diameter in the study (if absent, assumes this value is the baseline_sum)
timepoint_diam	The variable that represents the individual diameters at the later timepoint
timepoint_sum	The variable that represents the sum at the later timepoint
this_function	A label for error/warning messages (by default it is the name of this function)
label_string	The string to use for the result column

Value

A list, containing (1) the assessment (using RECIST v1.1 criteria) and (2) the supporting data

LisaHopcroft/CTutils documentation built on Oct. 7, 2021, 11:08 p.m.