calculate_dose_modification: Modify dose according to protocol schedule

In LisaHopcroft/CTutils: Helpful Functions for Clinical Trial Data Analysis at SCTRU (Public Health Scotland)

Description

This function takes an existing scale for dose modifications (as TRIAL.dose_scale) and, given an input value and a direction (+ for escalation and - for descalation), returns the modified dose.

Usage

calculate_dose_modification(
  value,
  direction = "+",
  dose_scale = TRIAL.dose_scale
)

Arguments

value	The current value.
direction	The direction (+/-) to move in on the dose scale (default="+")
dose_scale	The existing dose escalation/descalation scale for this trial.

Value

The new dose.

Examples

this.dose_scale = c( 1,2,4,8,16 )
calculate_dose_modification( 2 , dose_scale = this.dose_scale )
calculate_dose_modification( 16, "-", dose_scale = this.dose_scale )

LisaHopcroft/CTutils documentation built on Oct. 7, 2021, 11:08 p.m.