MalignantCellsFinder: MalignantCellsFinder Function identifies putative malignant...

In LunFlaer/DTCFinder: Malignant cells finder

Description

MalignantCellsFinder Function identifies putative malignant cells based on inferred CNV profiles of cells using two-component Gaussian Mixture Models fitted to 10X single cells expression profiles

Usage

MalignantCellsFinder(PathToData = ".", pvalue = 0.05, p_adj = 1e-06)

Arguments

PathToData	Folder with barcodes.tsv, features.tsv (or genes.tsv), matrix.mtx
pvalue	P value to define outliers relative to CD45-positive cells. Default = 0.05
p_adj	P value to define immune cells and malignant cells. Default = 1e-6

Value

a vector of predicted malignant cells

Examples

MalignantCellsFinder("outs/filtered_feature_bc_matrix/")

LunFlaer/DTCFinder documentation built on July 17, 2020, 4:26 a.m.