Man pages for Merck/simtrial
Clinical Trial Simulation
| as_gt | Convert summary table to a gt object |
| check_args | Check argument types, length, or dimension |
| counting_process | Process survival data into counting process format |
| create_cut | Create a cutting function |
| create_test | Create a cutting test function |
| cut_data_by_date | Cut a dataset for analysis at a specified date |
| cut_data_by_event | Cut a dataset for analysis at a specified event count |
| early_zero | Zero early weighting function |
| ex1_delayed_effect | Time-to-event data example 1 for non-proportional hazards... |
| ex2_delayed_effect | Time-to-event data example 2 for non-proportional hazards... |
| ex3_cure_with_ph | Time-to-event data example 3 for non-proportional hazards... |
| ex4_belly | Time-to-event data example 4 for non-proportional hazards... |
| ex5_widening | Time-to-event data example 5 for non-proportional hazards... |
| ex6_crossing | Time-to-event data example 6 for non-proportional hazards... |
| fh | Fleming-Harrington weighting function |
| fit_pwexp | Piecewise exponential survival estimation |
| get_analysis_date | Derive analysis date for interim/final analysis given... |
| get_cut_date_by_event | Get date at which an event count is reached |
| maxcombo | MaxCombo test |
| mb | Magirr and Burman weighting function |
| mb_delayed_effect | Simulated survival dataset with delayed treatment effect |
| milestone | Milestone test for two survival curves |
| multitest | Perform multiple tests on trial data cutting |
| randomize_by_fixed_block | Permuted fixed block randomization |
| rmst | RMST difference of 2 arms |
| rmst_single_arm | Calculate RMST for a single cut-off time point |
| rmst_two_arm | Calculate RMST difference |
| rpwexp | The piecewise exponential distribution |
| rpwexp_enroll | Generate piecewise exponential enrollment |
| sim_fixed_n | Simulation of fixed sample size design for time-to-event... |
| sim_gs_n | Simulate group sequential designs with fixed sample size |
| sim_pw_surv | Simulate a stratified time-to-event outcome randomized trial |
| simtrial-package | simtrial: Clinical Trial Simulation |
| summary | Summary of group sequential simulations. |
| to_sim_pw_surv | Convert enrollment and failure rates from 'sim_fixed_n()' to... |
| wlr | Weighted logrank test |
