rmst_single_arm: Calculate RMST for a single cut-off time point

In Merck/simtrial: Clinical Trial Simulation

Calculate RMST for a single cut-off time point

Description

Calculate RMST for a single cut-off time point

Usage

rmst_single_arm(
  time_var,
  event_var,
  tau,
  group_label = "Single Group",
  alpha = 0.05
)

Arguments

time_var	A numeric vector of follow up time.
event_var	A numeric or integer vector of the status indicator; 0=alive 1=event.
tau	A value of pre-defined cut-off time point.
group_label	A character of customized treatment group name.
alpha	A numeric value of the significant level for RMST confidence interval. Default is 0.05.

Value

A data frame of

• Cutoff time: same as tau;

• Group label: same as group_label;

• Estimated RMST;

• Variance, standard error, and CIs of the estimated RMST;

• Number of events.

Examples

data(ex1_delayed_effect)
data_single_arm <- ex1_delayed_effect[ex1_delayed_effect$trt == 1, ]
simtrial:::rmst_single_arm(
  time_var = data_single_arm$month,
  event_var = data_single_arm$evntd,
  tau = 10,
  group_label = "Treatment 1",
  alpha = 0.05
)

Merck/simtrial documentation built on April 14, 2025, 5:37 a.m.