NKI-CCB/RUBIC: Recurrent DNA copy number break detection to identify driver aberrations
RUBIC detects recurrent copy number aberrations using copy number breaks, rather than recurrently amplified or deleted regions. This allows for a vastly simplified approach as recursive peak splitting procedures and repeated re-estimation of the background model are avoided. Furthermore, the false discovery rate is controlled on the level of called regions, rather than at the probe level.
Getting started
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Package details |
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| Author | Ewald van Dyk (NKI), Nicola Bonzanni (eNPicom), Alvise Trevisan (eNPicom) |
| Maintainer | Lodewyk Wessels <l.wessels@nki.nl> |
| License | Apache License (== 2.0) |
| Version | 1.0.2 |
| Package repository | View on GitHub |
| Installation |
Install the latest version of this package by entering the following in R:
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