euadrReferenceSet: The EU-ADR reference set A reference set of 43 drug-outcome...

In OHDSI/MethodEvaluation: Package for Evaluation of Estimation Methods

The EU-ADR reference set A reference set of 43 drug-outcome pairs where we believe the drug causes the outcome ( positive controls) and 50 drug-outcome pairs where we believe the drug does not cause the outcome (negative controls). The controls involve 10 health outcomes of interest. Note that originally, there was an additional positive control (Nimesulide and acute liver injury), but Nimesulide is not in RxNorm, and is not available in many countries.

Description

The EU-ADR reference set A reference set of 43 drug-outcome pairs where we believe the drug causes the outcome ( positive controls) and 50 drug-outcome pairs where we believe the drug does not cause the outcome (negative controls). The controls involve 10 health outcomes of interest. Note that originally, there was an additional positive control (Nimesulide and acute liver injury), but Nimesulide is not in RxNorm, and is not available in many countries.

Usage

data(euadrReferenceSet)

Format

A data frame with 399 rows and 10 variables:

exposureId

Concept ID identifying the exposure

exposureName

Name of the exposure

outcomeId

Concept ID identifying the outcome

outcomeName

Name of the outcome

groundTruth

0 = negative control, 1 = positive control

indicationId

Concept Id identifying the (primary) indication of the drug. To be used when one wants to nest the analysis within the indication

indicationName

Name of the indication

comparatorId

Concept ID identifying a comparator drug that can be used as a counterfactual

comparatorName

Name of the comparator drug

comparatorType

How the comparator was selected

References

Coloma PM, Avillach P, Salvo F, Schuemie MJ, Ferrajolo C, Pariente A, Fourrier-Reglat A, Molokhia M, Patadia V, van der Lei J, Sturkenboom M, Trifiro G. A reference standard for evaluation of methods for drug safety signal detection using electronic healthcare record databases. Drug Safety 36(1):13-23, 2013

OHDSI/MethodEvaluation documentation built on July 3, 2023, 1:25 p.m.