calculateOL: Analyze Off-ladder Alleles
In OskarHansson/strvalidator: Process Control and Validation of Forensic STR Kits

calculateOL

R Documentation

Analyze Off-ladder Alleles

Description

Analyze the risk for off-ladder alleles.

Usage

calculateOL(kit, db, virtual = TRUE, limit = TRUE, debug = FALSE)

Arguments

`kit`	data.frame, providing kit information.
`db`	data.frame, allele frequency database.
`virtual`	logical default is TRUE, calculation includes virtual alleles.
`limit`	logical default is TRUE, limit small frequencies to 5/2N.
`debug`	logical indicating printing debug information.

Details

By analyzing the allelic ladders the risk for getting off-ladder (OL) alleles are calculated. The frequencies from a provided population database is used to calculate the risk per marker and in total for the given kit(s). Virtual alleles can be excluded from the calculation. Small frequencies can be limited to the estimate 5/2N.