peccary_pknca: PKNCA helper

In Peccary-PMX/PeccAnalysis: Analyse PK/PD dataset

PKNCA helper

Description

peccary_NCA compute basic NCA analysis (no extrapolation)

Usage

peccary_pknca(
  dataset,
  Time,
  conc,
  Subject,
  dose = NA,
  EVID = NA,
  AUC0_x = 0,
  computeMedian = T,
  route = NA,
  rate = 0,
  duration = 0,
  option = NA,
  outputExpr = F
)

Arguments

dataset	Dataset to analyze
Time	The name (unquoted) of the time column. Mandatory.
conc	The name (unquoted) of the observation column. Mandatory.
Subject	All the names (unquoted) of the grouping column separated by "+" (ID, YTYPE, nAdmin, any covariate....).
dose	Name of the dose column (unquoted)
EVID	The name (unquoted) of the evid column. Optional. Only line with evidcol = 0 will be kept
AUC0_x	Numeric input. Compute AUC from time 0 to time auc_0_X
computeMedian	Compute median of profile per Subject combination and time (avoid computational error)
route	Optionnal, either "intravascular" or "extravascular"
rate	Either name of the perfusion rate column or a number other of 0 for perf
duration	Either name of the perfusion duration column or a number other of 0 for perf
option	List of options to input in PKNCa, see their documentations
outputExpr	Output the expression (T), the result (F) or both ("Both")

Author(s)

Thibaud Derippe ([e-mail])

Peccary-PMX/PeccAnalysis documentation built on July 7, 2022, 5:27 a.m.