View source: R/anchor_residuals.R
Calculate genetic interaction scores by treating each guide as an anchor
1 | calculate_anchor_residuals(lfc_df, n_guides = FALSE, fit_controls = FALSE)
|
lfc_df |
data frame with the columns 'gene1', 'gene2', 'guide1', 'guide2', 'control1', 'control2', ... |
n_guides |
guides per gene if FALSE, then controls are not grouped into pseudogenes |
fit_controls |
if TRUE only use controls to fit linear model |
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