applyFilter: Constructing robust reference standards for Nof1 studies for...

Description Usage Arguments

View source: R/applyFilters.R

Description

referenceNof1 is the R implementation of the reference biomarker algorithm by (Zaim 2020)

Usage

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applyFilter(gs.mat = utils::data("mcf7"), expressionCutoff =30,
                   fold_change_window=c(1, 1.5), FDR.cutoff=0.1)

Arguments

gs.mat

a matrix of paired samples used to develop the reference standard. All paired samples must be adjacent

expressionCutoff

a scalar positive integer > 1 indicating the minimum count value of RNA-seq

FCCutoff

a scalar indicating minimum fold change cutoff

FDR.cutoff

fdr.threshold for determining which set of genes are DEGs in the reference standard


SamirRachidZaim/referenceNof1 documentation built on Oct. 24, 2020, 2:22 p.m.