Scale clearance by age for when enzymatic clearance is known at reference age.
1 | scale_enzymatic(out_ages, tot_scaled_recomcl, cypDb, cypCl, gender)
|
out_ages |
out_ages Ages for which the clearance needs to be calculated including reference age |
tot_scaled_recomcl |
Total Recombinant enzyme clearance at reference age in L/h/kg Liver |
cypDb |
Dataframe containing cyp datasets to scale measured clearance values from in-vitro to in-vivo |
cypCl |
Datafarame containing measured invitro enzymatic clearance. |
gender |
Gender, either "M" for male or "F" for female. Needed to get Liver weight |
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