Description Usage Arguments Value Examples
DMS Analysis
1 | runlimma(methylKit.obj, covariates, variance)
|
methylKit.obj |
methylBase object |
covariates |
covariate data frame |
variance |
cutoff for sites to use based on variance |
single site analysis (using limma's lmFit) – adjusts for covariates and weights methylation values based on log10(coverage)
1 | DMS<- runlimma(methylkit.obj,covariates,variance=0.75)
|
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