HumanNet: HumanNet

In ShandongUniversityZhanglab/DriverRWH: DriverRWH: Discovering Cancer Driver Genes by Random Walk on a Gene Mutation Hypergraph

HumanNet

Description

HumanNet is a probabilistic functional gene network of 18,714 validated protein-encoding genes of Homo sapiens (by NCBI March 2007), constructed by a modified Bayesian integration of 21 types of 'omics' data from multiple organisms, with each data type weighted according to how well it links genes that are known to function together in H. sapiens. Each interaction in HumanNet has an associated log-likelihood score (LLS) that measures the probability of an interaction representing a true functional linkage between two genes.

Usage

data(HumanNet)

Details

Each interaction in HumanNet has an associated log-likelihood score (LLS) that measures the probability of an interaction representing a true functional linkage between two genes.

Source

http://www.functionalnet.org/humannet/about.html

References

Insuk Lee, U. Martin Blom, Peggy I. Wang, Jung Eun Shin, and Edward M. Marcotte Genome Research 21(7):1109-21 (2011)

Examples

data(HumanNet)

ShandongUniversityZhanglab/DriverRWH documentation built on May 10, 2022, 2:47 a.m.