Comprehensive DMR analysis based on bimodal normal distribution model and weighted cost function for regional methylation analysis optimization. It captures the regional methylation modification by taking the spatial distribution of CpGs into account for the enrichment DNA methylation sequencing data so as to optimize the definition of the empirical regions. Combined with the dependent adjustment for regional pvalue combination and DMR annotation.
Package details 


Author  Sheng Li 
Maintainer  Sheng Li <[email protected]> 
License  MIT 
Version  0.6.1 
Package repository  View on GitHub 
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