Description Usage Arguments Value See Also Examples
Performs k-means clustering to assign signature to samples and performs enrichment analysis.
1 2 | snv_signatureEnrichment(maf, sig_res, minMut = 5, useCNV = FALSE,
fn = NULL)
|
maf |
an |
sig_res |
Signature results from |
minMut |
Consider only genes with minimum this number of samples mutated. Default 5. |
useCNV |
whether to include copy number events. Only applicable when MAF is read along with copy number data. Default TRUE if available. |
fn |
basename for output file. Default NULL. |
result list containing p-values
Other SNV analysis functions: snv_extractSignatures
,
snv_plotSignatures
,
snv_readprofile
,
snv_trinucleotideMatrix
1 2 3 4 5 6 | ## Not run:
laml.tnm <- snv_trinucleotideMatrix(maf = laml, ref_genome = 'BSgenome.Hsapiens.UCSC.hg19',
prefix = 'chr', add = TRUE, useSyn = TRUE)
laml.sign <- snv_extractSignatures(mat = laml.tnm, plotBestFitRes = FALSE)
## End(Not run)
|
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