1 2 3 4 5 |
gene_set |
a list of character vectors contains gene IDs of the query gene sets. |
back_ground |
a character vector contains the IDs of the background genes. |
orgDb |
an |
category |
a character specifying the gene ontology category, can be one in "BP", "CC", and "MF", default "BP". |
gene_key |
a character specifying the type of the gene ID, the available types of the keys can be find using |
min_bg_count |
term minimum number of occurence in background genes; default 1. |
max_bg_count |
term maximum number of occurence in background genes; default Inf. |
min_gs_count |
term minimum number of occurence in gene set genes; default 1. |
max_gs_count |
term maximum number of occurence in gene set genes; default Inf. |
EASE_Score |
whether or not use EASE score method. (a more conservative hypergeomatric test calculation used in DAVID) for more details please refer to https://david.ncifcrf.gov/helps/functional_annotation.html#fisher, default FALSE. |
pvalue_correction |
method used for multiple hypothesis adjustment, can be one in "holm", "hochberg", "hommel", "bonferroni", "BH", "BY","fdr", and "none". |
interpret_term |
whether to let the GO term readable, default FALSE. |
show_gene_name |
whether to attach readable gene names for each GO term, default FALSE. |
GO_Slim |
whether to run GSEA only on GO slim terms (a certain subset to GO terms), default FALSE. |
Slim_ss |
a character sting of GO terms that define the scope of GO Slim. if not provided, the GO slim would be the generic subset defined in : http://geneontology.org/ontology/subsets/goslim_generic.obo |
Exclude_self |
whether the GO slim terms of its own category i.e. remove terms of c("GO:0008150","GO:0005575","GO:0003674"), default TRUE; only applied when GO_Slim = TRUE. |
goea
conduct regular goea analysis with Fisher's exact test / permutation test.
a list
of data.frame
for GO exact enrichment result.
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