generate_graph: Build background PPI Network

In aaronwolen/dmGWAS2: A fork of EW_dmGWAS

Description

generate_graph constructs a node- and edge-weighted PPI network for function dms. This function is generally called by function dms. Typically users do not need to call it.

Usage

generate_graph(expr1, expr2 = NULL, network, geneweight)

Arguments

expr1	A data frame containing gene expression data from case samples. The first column is gene identifier (should be coordinate with the node symbol used in PPI
expr2	A data frame containing gene expression data from control samples. The first column should be the same as expr1
network	A data frame containing a symbolic edge list of the PPI network
geneweight	A data frame containing two columns: the first is unique gene identifier (should be coordinate with the node symbol used in PPI); the second is gene-based p-value derived from GWAS

Examples

## Not run: 
G<- generate_graph (expr1, expr2, network, geneweight)

## End(Not run)

aaronwolen/dmGWAS2 documentation built on May 10, 2019, 4:04 a.m.