sim.CC.data.ExE: Simulates case and controls

In agaye/ESPRESSO.ExE: Power Analysis and Sample Size Calculation for a environment-environment interaction model

Description

Generates affected and non-affected subjects until the set sample size is achieved.

Usage

sim.CC.data.ExE(n = NULL, ncases = NULL, ncontrols = NULL,
  max.sample.size = NULL, pheno.prev = NULL, e1.model = NULL,
  e1.prev = NULL, e1.mean = NULL, e1.sd = NULL, e1.low.lim = NULL,
  e1.up.lim = NULL, e1.OR = NULL, e2.model = NULL, e2.prev = NULL,
  e2.mean = NULL, e2.sd = NULL, e2.low.lim = NULL, e2.up.lim = NULL,
  e2.OR = NULL, i.OR = NULL, b.OR = NULL, ph.error = NULL)

Arguments

n	Number of observations to generate per iteration
ncases	Number of cases to simulate
ncontrols	Number of controls to simulate
max.sample.size	Maximum number of observations allowed
pheno.prev	Prevalence of the binary outcome
e1.model	Model of the 1st environmental exposure
e1.prev	Prevelance of the 1st environmental exposure
e1.mean	Mean of the 1st environmental exposure
e1.sd	Standard deviation of the 1st environmental exposure
e1.low.lim	Lower limit of the 1st environmental exposure
e1.up.lim	Upper limit of the 1st environmental exposure
e1.OR	Odds ratios of the 1st environmental exposure
e2.model	Model of the 2nd environmental exposure
e2.prev	Prevelance of the 2nd environmental exposure
e2.mean	Mean of the 2nd environmental exposure
e2.sd	Standard deviation of the 2nd environmental exposure
e2.low.lim	Lower limit of the 2nd environmental exposure
e2.up.lim	Upper limit of the 2nd environmental exposure
e2.OR	Odds ratios of the 2nd environmental exposure
i.OR	Odds ration of the interaction
b.OR	Baseline odds ratio for subject on 95 percent population centile versus 5 percentile. This parameter reflects the heterogeneity in disease risk arising from determinates that have not been measured or have not been included in the model.
ph.error	misclassification rates: 1-sensitivity and 1-specificity

Value

A matrix

Author(s)

Gaye A.

agaye/ESPRESSO.ExE documentation built on May 10, 2019, 7:30 a.m.