Description Usage Arguments Value Author(s)
Simulates errors and adds it to the true data to obtain observed data. The alleles simulated by the function sim.geno.data are randomly misclassified and used to form new genotypes that represent the observed genotypes.
1 2 |
allele.A |
Allele A |
allele.B |
Allele B |
geno.model |
genetic model; binary=0 and additive=1 |
MAF |
minor allele frequency of the SNP (in ESPRESSO this is the frequency of the 'at risk' allele) |
geno.error |
a vector with two values, the misclassififcation rates related to the sensitivity and specificity of the assessment of the alleles, i.e. 1-sensitivity and 1-specificity |
a dataframe that contains the below data:
observed.genotype
observed genotypes
observed.allele.A
observed A alleles
observed.allele.B
observed B alleles
Gaye A.
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