sim.pheno.bin.GxG: Generates phenotype status

In agaye/ESPRESSO.GxG: Power Analysis and Sample Size Calculation for a gene-gene interaction model

Description

Generates affected and non-affected subjects

Usage

sim.pheno.bin.GxG(num.obs = NULL, disease.prev = NULL, genotype1 = NULL,
  genotype2 = NULL, interaction = NULL, subject.effect.data = NULL,
  geno1.OR = NULL, geno2.OR = NULL, int.OR = NULL)

Arguments

num.obs	Number of observations to generate per iteration
disease.prev	Prevalence of the binary outcome
genotype1	Exposure data for 1st genetic determinant
genotype2	Exposure data for 2st genetic determinant
interaction	data
subject.effect.data	Subject effect data, reflects the heterogenity in baseline disease risk
geno1.OR	Odds ratios of the 1st genetic determinant
geno2.OR	Odds ratios of the 2st genetic determinant
int.OR	Odds ration of the interaction

Value

A dataframe of phenotype

Author(s)

Gaye A.

agaye/ESPRESSO.GxG documentation built on May 10, 2019, 7:31 a.m.